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Cystic fibrosis (CF) is a genetic disorder that affects mostly the lungs, but also the pancreas, liver, kidneys, and intestine. Long-term issues include difficulty breathing and coughing up mucus as a result of frequent lung infections. Other signs and symptoms include sinus infections, poor growth, fatty stool, clubbing of the fingers and toes, and infertility in males, among others. Different people may have different degrees of symptoms. As the pancreas becomes blocked with mucus, enzymes required for digesting food cannot reach the stomach. People with cystic fibrosis often need to take more than 50 tablets a day to help digest food and keep respiratory symptoms in check Understanding and treatment of cystic fibrosis have come so far since the condition was first described in the 1930s. More than half of people with cystic fibrosis in the UK will now live past 47, and babies born today are expected to surpass that. With more than 50% of the CF population in work or education and many people with cystic fibrosis having families of their own, you can see evidence of a brighter future wherever you turn. Part of this is down to the increasingly personalized healthcare available for people with cystic fibrosis. We are fighting to lift all of the limits that cystic fibrosis places on people with the condition, so that they can live long and healthy lives.